Presenter:Wolfgang J. Parak
Philipps Universität Marburg, Marburg, Germany & CICBiomagune, San Sebastian, Spain
Time:Jan.20th 2015(Tuesday)9:00am
Venue:Research Institute of Micro/Nano Science and Technology 2-103
Colloidal nano- and microparticles are incorporated by cells. Uptake and also toxic effect can be correlated with physicochemical parameters of the particles. Methods and examples will be discussed.
References:
R. Hartmann, M. Weidenbach, M. Neubauer, A. Fery, W. J. Parak, „Stiffness-dependent in vitro uptake and lysosomal acidification of colloidal particles”, AngewandteChemie, in press, DOI: 10.1002/anie.201409693.
D. Hühn, K. Kantner, C. Geidel, S. Brandholt, I. De Cock, S. J. Soenen, P. Rivera Gil, J. M. Montenegro Martos, K. Braeckmans, K. Müllen, G. U. Nienhaus, M. Klapper, W. J. Parak, "Polymer-coated nanoparticles interacting with proteins and cells: Focusing on the sign of the net charge", ACS Nano7, 3253–3263 (2013).
M. Nazarenus, Q. Zhang, M. G. Soliman, P. del Pino, B. Pelaz, S. Carregal-Romero, J. Rejman, B. Rothen-Rutishauser, M. J. D. Clift, R. Zellner, G. U. Nienhaus, J. B. Delehanty, I. L. Medintz, W. J. Parak, “Interaction of Colloidal Nanoparticles with Mammalian Cells: What Have We Learned Thus Far?”, Beilstein Journal of Nanotechnology5, 1477–1490 (2014).
W. Kreyling, A. M. Abdelmonem, A. Wenk, D. Jimenez de Aberasturi, A. Zulqurnain, J.-M. Montenegro, S. Hirn, I. Ruiz de Larramendi, T. Rojo, N. Haberl, G. Khadem-Saba, W. J. Parak, "In vivo integrity of colloidal nanoparticles", Nature Nanotechnology, in revision.
Bio:
1989-1997 General Physics studies at the TechnischeUniversitätMünchen, Germany
1995-1997 Diploma thesis ("Diplomarbeit") at the Technische Universität München, Germany
1997-1999 Graduate student at the Ludwig Maximilians Universität München, Germany,
2000-2002 Postdoc at the Department of Chemistry at the University of California at Berkeley, California, USA,
2003-2006 Leader of a Junior Research Group (Emmy-Noether fellowship of the German Research Foundation (DFG),
2005 Temporary position as Associate Professor for Physical Chemistry at the Department of Chemistry and Pharmacy at the Ludwig Maximilians Universität München, Germany for the Summer Semester
since 2007 Full Professor (chair) for Experimental Physics at the Philipps-University of Marburg, Germany
since 2013 in addition head of the Biofunctional Nanomaterials Unit at CICbiomaGUNE, San Sebastian, Spain
2009 "Nanoscience" - award 2008 from the Association of Nanotechnology-Centres Germany (AGenNT)
since 2010 Associate Editor for ACS Nano from the American Chemical Society
2011 ranked #59 in Top Materials Scientists of the past decade by Essential Science Indicators (http://science.thomsonreuters.com/products/esi/)
2012 Awarded Chinese Academy of Sciences Visiting Professorship for Senior International Scientists
2014 highly cited in the category materials sciences (http://highlycited.com/)
2014listed in “The World’s Most Influential Scientific Minds: 2014” (http://www.sciencewatch.com)
present h-index: 55